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Cersad t1_iw3sn6i wrote

Reply to comment by triffid_boy in How do medical researchers obtain lab animals with diseases like specific forms of cancer which arise spontaneously? Do they raise thousands of apes and hope some eventually develop the disease? by userbrn1

Right, but primates are also the only animal model that is appropriate for more complex etiologies. A genetically-defined model marmoset or macaque of neurological disorders would arguably be a better model than any rodent could aspire to.

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FiascoBarbie t1_iw43vel wrote

For some things. Rodents with Parkinson’s like syndromes have most of the same stuff as humans. Linguistic aphasia’s not so much.

What particular neurological disorders do you think are not well modeled in rodents and what would the better alternative be ?

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Welpe t1_iw4td6q wrote

Linguistic aphasia not so much?! So the rodents could speak perfectly? And here I was thinking all rodents had problems communicating linguistically!

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FiascoBarbie t1_iw5j82l wrote

No, obviously rodents don’t have language so they are not a good model for language problems.

That wasn’t clear when I said they weren’t a good model for linguistic aphasia?

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Delta9ine t1_iw6xhcw wrote

Nah. It was very clear to anyone following the thread who has even the most basic reading comprehension skills.

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triffid_boy t1_iw40zwc wrote

I mean sure, but you said could feasibly be studied since those recent papers - they were feasible models for a long time now.

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Cersad t1_iw422d5 wrote

I thought the CRISPR in primates only dated back to 2018-ish, but my memory could be a bit hazy. In the world of NHP research, six years is less than the useful life of the rhesus macaques I've seen in labs.

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