sunlitupland5 t1_j761skf wrote
Need also to consider gut microbiome diversity when looking at immune reaction. Research is still in early stage but theoretically the greater the diversity the less likely immune system is to over react to a perceived threat
Imaginary-Benefit-54 t1_j76rf6y wrote
How would one go to explore broadening the diversity?
raziel686 t1_j778img wrote
Be weary of generalities online. Gut biome is an interesting area of study, but we haven't done enough studies and what you hear are mostly small studies that get played up in the media like they are hard science when really they are just to help direct and improve further studies. They were never meant to set any guidelines or direct people to action. We aren't there yet, and with how different everyone's body is with this, it'll likely be a while before anything definitive is suggested to people.
So to answer your question, we don't know. Because gut biomes vary significantly from person to person and will even change over time, and we wouldn't know what you need or don't need or if you're fine as is, it would require a lot of work to try and figure out what might help you if you're having problems. You'd need testing done of a clinical environment.
If you are having gut issues though, consuming good live culture bacteria found in things like yogurt is beneficial. Greek yogurt is the one you hear about most because it has less sugar. This is a standard reccomendation for people going on antibiotics as they don't discriminate which bacteria they kill and putting ones we know help digestion back can reduce side effects of antibiotics.
Imaginary-Benefit-54 t1_j77c8dw wrote
I really appreciate the thorough response and taking the time thank you! Very interesting indeed and great to have a perspective that isn’t just the medias take.
What would be good sources worth trying for someone who doesn’t get on with the typical pro biotics which dairy based?
raziel686 t1_j77irwp wrote
No problem. There are definitely options for you. Off the top of my head, Kombucha is a big one. Fermented foods like kimchi and saurkraut. Miso is another one. Generally any good probiotic will need to be kept cold, though there are exceptions. Be wary of room temperature pill based ones, their efficacy is iffy.
Imaginary-Benefit-54 t1_j77rxrd wrote
Thank you! I really do appreciate it and will step off from here and investigate further. You’re the best!
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perta1234 t1_j77juof wrote
Not sure about importance of that compared to larger parasites. One famous ethical problems in science was that people were given infection of... I think it was pig roundworm in stomach. It cannot procreate in human. But the people lost their allergies. So now the ethical question was, do people participating experiment get to keep the worm that is beneficial to them. Anyway, one hypothesis is that allergies are due to lack of parasites when we have a system to fight against them.
CrazyisNSFW t1_j77qfce wrote
Just adding to your reply. I found this paper outlining different, competing hypotheses, and parasite hypothesis is only one of them:
The evolution of IgE-mediated type I hypersensitivity and its immunological value
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