It’s more confirmation, but it’s actually wild how little evidence actually exists - especially in humans - for a serotonergic deficiency in depression. Like there must be some link given the relatively decent efficacy or SSRIs, but the hard evidence is way thinner than most people realize.
DjangoUnhinged t1_iv6efbg wrote
Reply to comment by doctoreldritch in BRAIN SEROTONIN RELEASE IS REDUCED IN PATIENTS WITH DEPRESSION: A [11C]Cimbi-36 PET STUDY WITH A D-AMPHETAMINE CHALLENGE. - Biological Psychiatry by chilladipa
It’s more confirmation, but it’s actually wild how little evidence actually exists - especially in humans - for a serotonergic deficiency in depression. Like there must be some link given the relatively decent efficacy or SSRIs, but the hard evidence is way thinner than most people realize.