Balthasar_Loscha
Balthasar_Loscha t1_j8syjub wrote
Reply to comment by AnnexBlaster in According to a study on 12,211 patients, aspirin is just as effective at preventing blood clots as low molecular weight heparin, but it costs less and is easier to administer by giuliomagnifico
Aspirin as a preventative for COVID-related clotting in a male? Not your area, but maybe you heard something?
Balthasar_Loscha t1_iy5nsv7 wrote
Reply to comment by BandComprehensive467 in SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial by BandComprehensive467
>It was observed that salicylic acid in plant based dieters was potentially higher than those taking low dose aspirin and typically much higher than other subjects.
No, circulating SA is a hundred times lower in vegetarians and non-vegetarians compared to consumers of low dose aspirin.
Balthasar_Loscha t1_iy5jyy2 wrote
Reply to comment by BandComprehensive467 in SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial by BandComprehensive467
"Results: Salicylic acid was detected in every serum sample analysed. Higher serum concentrations of salicylic acid were found in vegetarians than non-vegetarians: median concentrations of 0.11 (range, 0.04-2.47) micromol/litre and 0.07 (range, 0.02-0.20) micromol/litre, respectively; the median of the difference was 0.05 micromol/litre (95% confidence interval for difference, 0.03 to 0.08; p < 0.0001). The median serum concentration of salicylic acid in patients taking aspirin (75 mg daily) was 10.03 (range, 0.23-25.40) micromol/litre, which was significantly higher than that found in non-vegetarians and vegetarians."
The contribution of diet to concentrations of SA is neglible, and not useable as a replacement for low dose Aspirin
Balthasar_Loscha t1_iy5fdjn wrote
Reply to comment by BandComprehensive467 in SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial by BandComprehensive467
>Yeah salicylic acid is very high in some plants, cumin I believe has the highest at ~1% by weight if I remember correctly.
The intake of SA in a regular diet, even with a high amount of plant intake, is neglible. Rare outliers like the alleged cumin should be ignored.
Balthasar_Loscha t1_iy4nhf5 wrote
Reply to comment by BandComprehensive467 in SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial by BandComprehensive467
Any information on salicylic acid amounts in plants? They are very very low, iirc. Arginine is effective as a NO donor if it is taken apart from meals. Animal-based, restaurant-type of diet has the best precedence worldwide, and plant-based diets, 3rd World-diets, unfortunately the worst :(
Balthasar_Loscha t1_iy2jdla wrote
Reply to Enhanced replication of SARS-CoV-2 Omicron BA.2 in human forebrain and midbrain organoids by wmdolls
I don't want to be a negative nancy, but apoptosis of our hueman forebrains sounds not ok!
Balthasar_Loscha t1_iy2j1qc wrote
Reply to Amygdala connectivity predicts ketamine treatment response among patients with anxious depression by chrisdh79
The Ketamine effect also seem to be dependent on rising IGF-1 level in the CNS, atleast in rodents. Maybe Somatropin injections are the real deal here.
Balthasar_Loscha t1_iy2ebv9 wrote
Reply to comment by neuro__atypical in SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial by BandComprehensive467
Noted, but better to not get clots in the first place though.
Balthasar_Loscha t1_iy2dtea wrote
Reply to Pregnant women exposed to alcohol are at a significantly greater risk of developing post-partum depression, meta-analysis shows. by Respawan
>post-partum depression
..is also associated with lowered DHA/EPA, and lowered ferritin, implicating moderate to severe iron deficiency.
Balthasar_Loscha t1_iy1xnuy wrote
Reply to comment by ABena2t in Obesity Is Now the Top Modifiable Dementia Risk Factor in the US (July 2022) by True_Garen
Diabetes causes wasting of vitamins in the urine, lessened uptake of DHA into the CNS, very high oxidative stress, lessened production/utilization of energy, and severe hormonal disorders, the major ones like E, Prog, Thyroid, DHEA, T.
Balthasar_Loscha t1_iy1qnsj wrote
Reply to SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial by BandComprehensive467
Oral L-Arginine, which is another general nitric oxide (NO) donor, at ~2x2000 mg/d, was shown to improve endpoints like survival in a rather big way, iirc. Low dose Aspirin at 80-150 mg/d reduces the clotting effect of Covid- 19 too, which likely reduces longer term tissue damage.
Balthasar_Loscha t1_ircpd3q wrote
Reply to High-fat diet induces depression-like phenotype via astrocyte-mediated hyperactivation of ventral hippocampal glutamatergic afferents to the nucleus accumbens - Molecular Psychiatry by Meatrition
>High-fat diet
..is a misnomer and actually describes high-carb+high-fat+caloric surplus. This isn't the effect of a ketogenic diet.
Balthasar_Loscha t1_j8vs7q9 wrote
Reply to comment by andygchicago in The antidiabetic drug metformin aids bacteria in hijacking vitamin B12 from the environment through RcdA (Jan 2023) by basmwklz
Does he consume all co factors, which are basically all nutrients, for erythropoiesis?