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pre-DrChad t1_j6fltqk wrote

Reply to comment by Verzingetorix in How rapidly will ai change the biomedical field? What changes can be expected. by Smellz_Of_Elderberry

He did mention in silico trials so I’m guessing he means being able to simulate human clinical trials so we can make it move faster. Not even close to possible now since we can’t simulate a human but perhaps in the future

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Verzingetorix t1_j6fq3kx wrote

Like you say, such thing doesn't exist. Assessing how much impact AI will have in medicine by speculating about a fictional tool is going to devolve to assumptions on top of assumptions on top of assumptions.

And I hardly believe drugs and therapies will ever be approved based on simulated data.

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pre-DrChad t1_j6fu13g wrote

That’s pretty much what this sub is. We are all speculating what AI will do in the future. Do you believe the singularity is possible? If so, it’s an odd statement to make that therapies won’t be approved based on simulated trials. I doubt the FDA or any such regulatory bodies will even exist in the future. What’s the need for human regulations when we have super intelligence far beyond our own?

We already have organ on a chip models, so we already have the building blocks for simulating a human. At the point where trials on a simulated human can predict results as well as human clinical trials, I bet we stop using human clinical trials.

Since you work on human clinical trials, you would know that humans are very diverse and not every human responds the same way to a treatment. So it’s not like human clinical trials are even close to perfect. We can use technology to move past human clinical trials

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Verzingetorix t1_j6fxl53 wrote

Yes, but AI exists already and has been in use in biomedical research for a while. In-silico clinical trials does not.

We can speculate about the first, but not how the first will do in light of the second. Especially when we would have to also come up with a reasonable argument on how would simulated trials even get approved.

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pre-DrChad t1_j6g65h2 wrote

It will get approved when it is more efficient, less costly, and accurate than human clinical trials. Which will happen inevitably if we do reach the singularity

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