midge_rat t1_j1uwby0 wrote
Reply to comment by Q8DD33C7J8 in Nerve block (an injection around a major sensory nerve for the shoulder) is an effective treatment for painful shoulder condition by giuliomagnifico
Is your husband a redhead by any chance, or have a redheaded parent?
Q8DD33C7J8 t1_j1wrsu0 wrote
He had a red cast to his hair as a child
WonkyHonky69 t1_j1xa9b0 wrote
This is probably not the reason. As much as I’m aware, the red hair anesthetic resistance was tested discovered for inhalational anesthetics, which do not have the same mechanisms of action as local anesthetics.
The real answer to your question could probably better be answered by an attending anesthesiologist (I’m only an intern), but you’re asking hours vs days as if all nerve blocks are created equal. They are not. Some local anesthetics last longer than others and there is an element of proceduralist dependence (in the case of a few hours vs 24 hours like OP stated). What the other commenter was talking about (weeks) is almost certainly a steroid injection, which is intended to reduce inflammation around the nerve, which will indeed last weeks. A local anesthetic nerve block for a surgery will not.
Q8DD33C7J8 t1_j1xau1o wrote
I know that's his red hair isn't a contributing factor in why his meds don't work.
midge_rat t1_j1wy0hz wrote
DeadlyInertia t1_j1yul8y wrote
Seems like this study uses desflurane, an inhaled anesthetic. Good study but nerve blocks are done using injectables
midge_rat t1_j1yzfli wrote
The results have been replicated with Novocaine and lidocaine
Q8DD33C7J8 t1_j1x89sd wrote
Cool thanks
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