I've done it. It was extremely difficult. You plan to read or get work done on the train but it's not always possible. Sometimes I'd stand most of the way. WiFi doesn't actually work so prepare to rely on your phone. The schedule isn't so hot so try not to miss your train home. All that said, it's doable for a limited time. After two years I really resented all the time I was losing to the commute.

Definitely consider how close the Boston station is to work, too. Commuter rail took about an hour in but getting on the green line from there blew another hour due to incredibly unreliable trains. Same thing in reverse, often missing the commuter train due to trolley issues. Just be prepared to have to kill some time...I did get to read a lot more!