Wow..just starting the shots in May. Allergist says by next year I should be doing better. First time doing this. He also said for me to invest in a good Hepa filter for my basement. ( Drinking area). Just started seeing mine in Jan. I jog 4-5 days a week and kept getting sick in the winter and summer. After extensive blood work and tests the culprit was the environment ( along with all grass and trees know to man..and shellfish. Oh..and cock roaches and mice.). Think that's it