It will really come down to your budget. I'd agree with your estimate on a mortgage payment of up to $3300, if you're pushing $450k with the purchase price. You said you have a monthly net income of $7500. So after making a $3300 mortgage payment, you'd have $4200 left. So the question is.....can you cover all your expenses and meet your savings goals with the remaining $4200/month? Without other significant debt, or general spending issues, it seems like you should be able to afford that.