Submitted by Chairman_Mittens t3_y96dfg in askscience
I was thinking about this while rising my mouth out with mouthwash this morning. Why does alcohol kill 99% of bacteria in my mouth, but not the cells that make up my cheeks, gums and tongue?
Isn't a single cell essentially the same basic structure as a bacteria, just joined together with other cells? Or am I actually killing millions of cells every time I rinse, but they regrow each time?
regular_modern_girl t1_it3x4qt wrote
It does kill cells in our body to some extent, like high concentration ethyl alcohol (like 90% or higher) can cause mild chemical burns in your mouth if you drink it neat. Not to mention the scarring of the liver (although tbf that’s more because of acetaldehyde, the fairly heavily toxic chemical ethanol gets mostly metabolized into).
This being said, it mostly is just a difference of scale; we not only have way more cells in our bodies, but eukaryotic cells are many times larger than (most) bacteria (this obviously varies a lot, but generally it is the case), so they’re far more vulnerable to damage or death by chemical means unless they’re specifically adapted against it.
But I guarantee you, if you somehow exposed every cell in your body at once to a high volume of 99% ethanol, you would not survive it either. The outer membranes of our cells are mostly just a thin film of lipids which organic solvents like ethanol can dissolve, and we don’t even have cell walls like bacteria do to add an extra layer of protection, it’s just that we normally only come into contact with alcohol in comparatively small amounts in a diluted form.
EDIT: also, should probably be mentioned, mouthwash usually does contain other antibacterial ingredients besides just ethanol, and if you just used, say, vodka as mouthwash, it would likely kill some bacteria in your mouth but overall not be nearly as effective (plus everyone would think you were a drunk).