In hindsight I should have used a better example to illustrate the point that the apparent durability of a covalent bond also depends on a relative free energy, where that delta can be highly dependent on environment, which in turn means that any ranking of bond strengths implicitly assumes some environment. I could have used, as you note, a host of other examples rather than a biological process with multiple intermediates etc. Since I stand by my bigger point in that comment, and it would be a substantial edit to correct the details, I’ll hope you’re helpful corrective will suffice if a fellow redditor wishes to dig into the details. Thanks.