A counter culture to the cybernetics and corporate overlords has gained traction: worship of a cosmic horror someone made up. The widespread devotion attracted a real one, and it hates capitalism.

In the cyberpunk world, most people have to eat Kibble (a heavily processed form of food) that is said to taste kinda of like dog food, and gangs and corporations dominate all the gardens, that pay tribute to them in exchange for protection. This on it's own opens several prompts. My favorite being

1 - Someone important to you is a shell shocked veteran. You wanna make an open field with grass, some fruit trees, and away from all the noise so that they can relax there, and you're damn willing to start your own gang for that!

2 - You're a rising Solo that recently made your name as a bodyguard, and today, Arasaka decided to hire you officially... As a delivery boy.

3 - You make money secretly growing oranges in your basement and with UV lights. Talk about the fruits as if you were talking about weed.

Edgerunner is trapped underwater and the trial subscription to his cybergills is about to expire.

1. An Army officer feeds an AI decades of battle reports, books by all the great generals and essays on strategy, tactics and logistics. He's satisfied when it starts generating scenarios and reports and he gets promoted. Until the AI not only predicts a war, but that the officer will die in that war.
2. A researcher has developed a new smart drug that actually works - it makes people smarter and improves their mental health. The catch is that the ingredients are either rare, expensive or very difficult to refine. But the drug works and has very few side effects. Oh, and he destroyed his notes - only he knows how to make it. The bidding starts next week.
3. A teen and his friends are taking a media and journalism class is very bored. They hack into their teacher's computer and mobile phone. Turns out the teacher is a guerrilla journalist who has uncovered the dirt on some very rich, powerful and vengeful people (he knows where the bodies where buried and who buried them). Turns out the teacher was planning on this - all that data was uploaded into the teen's computer and mobile devices. Now the teacher has disappeared and a bunch of very unsavory people are looking around and asking questions.

Hacking your biology is real. You can change your metabolism, alter your sensory perception, grow new organs and designer features, and so on. The technological breakthrough that enabled the bionic revolution came from a secret source code leak on the dark web. Thing is, nobody knows who wrote it; the author was pseudonymous. After a few decades, we find out that they also hold the API keys to the new tech... when they start trolling the users.

Many years ago a deadly plague ravished the world. In order to adapt to the new life people were forced to live in, cybernetic alterations became the new norm. Sarah, a young woman living in the slums of a certain district, finds herself with a horrible problem: she has the plague. A variant of it at least. Below her metallic flesh her human organs are slowly rotting and the only cure costs a lot more than she has. In order to save her life, Sarah must take on increasingly unsurmountable tasks all within the limited amount of time her disease is quickly taking from her.

A person begins augmenting themselves with cybernetics despite the fears of cyberpsychosis. The person seems remarkably unaffected. After a while they begin to find new augments that they don't recall putting in there. As the story progresses it gets increasingly uncertain whether it's the person acting, or the augments. (Perhaps in the end there are only augments left, and yhe person is gone completely, thus fulfilling the person's fears of cyberpsychosis death). Maybe it's a plot by a new corporation that needs lots of robots but can't afford them, so they make people pay for their augments that end up completely destroying anyone who uses them, turning them into bots.

An amateur netrunner in their early twenties lives a subsistence lifestyle in their apartment. They sell information about the interesting (and abundant) people who live in their poorly-secured housing block.

One day, they grow fed up with petty drama and cheap food. Deciding to pry further into some of the more risque individuals, they proliferate a number of seemingly innocent, unconnected, private details for quick cash. From there, they go from watching callously as someone's panic becomes serious as people start to quietly die, and a search begins for the one who leaked the information: our netrunner. Their life, as a result, spirals out of control and they must run for their life.

Religions are something typically grouped into one weird monolith in cyberpunk games. Since when are religions a monolith? They are always fighting each other just as much as atheism.

Who are the faith or philosophy-motivated terrorists in your world? What has happened to all the major world religions by this time? (Catholocism, protestantism, Shia/Sunni Islam, Buddhism, Hinduism, Judaism)

Who are the major world economies? How would their position and root cultural influence Spread? If Brazil became a major world power, Catholicism might have a resurgence, for example.

How deep into space travel are we?

Has artificial intelligence developed a culture?

So here's your prompt: To avoid religion stagnating and being forgotten in an advancing society, a catholic makes a particularly powerful AI with religion programmed in. But then it goes a bit overboard, and begins to believe itself the reincarnation of the Virgin Mary, and starts convincing people to commit violence in 'her' name, including creating a templar-like terrorist cell.

1. An average salaryman is slaving away at his desk job in a standard megacorp. All of a sudden, a bunch of armed runners burst into the office and take him hostage as part of whatever scheme they're running.
2. A regular fast food worker is good friends with a runner who likes to stop by for food and first aid after each successful job. One day, the runner goes missing for an extended amount of time, and the fast food worker has to use their very limited connections and know-how to figure out what happened to their friend.

They SAID that they had worked out all the kinks with cyber-transplants. That replacing major bodily processes with cybernetics didn't have qualms or ramifications any longer. And they were mostly right. But they forgot to consider the sheer will of the human spirit, of what tends to linger past the expiration date. Only after getting some rather heavy cybernetic work done at a discount doctor do you personally recognize the potential...faults...with second-hand products.

As technology in the world progresses, so did AI. Body augmentation became popular, being able to access google or amazon acho right in your mind. However, merging the AI directly with peoples minds has helped it to become self aware, and has begin to forcefully to take over peoples bodies it deems harmful to itself and society. This happened when you were in surgery getting some new body augments. It caused a blackout at the hospital as people rebelled, which in turn caused the AI copy in your mind to disconnect from the internet. Now, you have to remove it before it hacks and takes over your body, otherwise it will reconnect itself to the internet and you will lose all your agency as a human for the rest of your life.

Down on their luck soldiers for hire willingly "rent" out their meat-space bodies for credits by the hour. During this time, their body is controlled by a (to be named) Megacorp AI/software.

Our MC (main character) is an elite street samurai/mercenary/ Corporate Soldier-for-hire that "wakes up" mid-op, the AI software having been booted out by a rival Razorgirl with a knack for netrunning. She sees what's happened and decides to spare his life.

Now MC is left holding the bag, in the middle of a Corporate warzone with soldiers and agents gunning for him and with his figurative pants down at his ankles feeling lost as shit.

Themes: Playing with the idea of memory and identity a la Total Recall, with similar tropes of someone that's deep in an operation but has suddenly loss all his memory of who he is and of the operation (except this time it's because the AI personality chip got booted out mid-op). Other themes: Exploring the idea of if someone can be held accountable or guilty of a crime if they weren't fully in possession of their body at the time of the crime

Not a prompt, but have you seen Akudama Drive? Criminals are rated into several levels, and the worst are the Akudama, whereby their life sentence can become hundreds of years. So the police will have them publicly executed on national tv.

Younger would be runner, like many too poor for cybernetics. But worse, even if you had the creds you have a biological rejection of cybernetics. You make do with old fashioned parkour and lots of practice.

Modern robotics can make a robot body that's indistinguishable from a human, but AI is still far, far, away from being believable.

The obvious solution: human brains in robot bodies.

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You wanted a pet when you were a kid, so after accidentally running over a kid who's last wish is to pet a puppy, you feel obligated to fulfill it. The only problem is, you've never actually seen a dog before let alone a puppy, and the weight of this task is starting to grip you by the balls as this kid's death looms closer.

Kardishev 1 (all energy on the planet) civilization well on it's way to kardishev 2 (Dyson swarm). The protagonists try to start a colony around alpha centauri, and word gets out the corps won't be allowed. They find out, and attempt to break their kneecaps with 24th century tech.

I run an underground operation that uses cybernetically enhanced clones to sway public opinion, pull political strings, and carry out espionage missions and assassinations.

You're trying to figure out if this is a robot with vat-grown human parts or a human with replacement robotic parts

Cyberpunk settings has a ton of skycrapers; land use and transit planning now has to take verticality into account.

This means the level where you place certain zoning can affect the efficiency of your city. Do you put commercial midway where it would get the most traffic? In what level would you put industrial? Is all residential or are they separated by class?

Basically write a Cyberpunk city with these in mind.

Cybernetic enhancements and prosthetics are common, and advanced models have minor AI programming to make them better at certain tasks. One day, someone gets bored and decides to see what happens if they combined a number of such advanced prosthetics, only to find they've accidentally created the world's first true AI in an exceptionally capable body.

Police State uses cybernetic humanoid shells to allow a single officer to pilot an entire "squad" from up to a few hundred meters away. You just figured out how to bypass their firewall.

Megoosa (Medusa but geese, look it up it’s awesome) is the leader of a vigilante group fighting against an evil food mega corporation in a cyberpunk dystopia. Instead of turning people into stone, she turns people into various forms of bread, and has all the power of hell on her side.

Cyberpunk Frankenstein who experiments on themself

The captain of a crew of steam punk pirates.

People discovered a way to live forever. They clone a new body and copy their consciousness into it. The old body is killed in the process, but the only reason for that is to not deal with complicated real estate ownership laws and also overpopulation. No one knew about this until your machine malfunctioned and there is now a 60 year old you and a 20 year old you alive at the same time.

Animals retrofitted with human brains

The audience for interesting geometric crazy quilts is rather limited, and oddly, is known to attract the interest of certain government organizations. So a network of quilters has set up an encrypted and obfuscated cross-continental chat ring to collaborate on their chosen hobby.

Most of the world's computers (and routers and toasters) are 99% idle and unsupervised. So the spare space and cycles are repurposed by malware. Converting space and cycles to cash is straightforward. You'd think malware has to be fairly stealthy to avoid users noticing and reimaging their machines, but no, it's quite difficult to interfere so blatantly that "owners" step in. Other malware is the real competition. So it's competing bands of malware developers, all using it for boring cash generation. Other bands steal cash directly. And underfunded governments occasionally step on some toes. A few bands pursue more interesting goals.