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Ok_Anywhere_1791 t1_j4o93p3 wrote

No, you won't hear about it. You don't sound like the kind of person to seek information out or to keep up with further developments. It goes against a cynical philosophy, after all.

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ConfirmedCynic t1_j4oahvx wrote

Here I am, with a list of developments I've kept hopeful track of, but ok.

Reasons for hope:

  • John Goodenough's battery

  • XNRGI's battery

  • Lyten lithum sulfur batteries

  • solar shingles

  • SpaceX

  • magnetic reconnection space drive (Fatima Ebrahimi) (2021) hopes to have a first prototype soon

  • Mach Effect

  • "augmented reality", HoloLens

  • hot fusion companies (including Apollo Fusion)

  • Quaise Energy geothermal power

  • detonation engine for rockets

  • NMN

  • Gaianneschi fatty acid drug delivery (2019, no news since)

  • DpC

  • TREM

  • ISRIB: small molecue cognitive enhanc

  • PAMPS hydrogel for cartilege = Bolt Biotheraputics's ISAC anti-cancer therapy

  • Alkahest young blood plasma for brain healing

  • αKLOTHO and TGFβR2 treatment for osteoarthritis

  • NaNots (NaNotics) - subtractive nanoparticles

  • Senisca - correcting dysregulation of RNA processing (2021)

  • retrolytics (2020, Andrew Gudkov)

  • GlyNAC (Rajagopal Sekhar)

  • LyGenesis (2022, starting first human trial)

  • Lomecel-B

  • senolytics

  • David Sinclair (Harvard)'s anti-aging pill (SOCOM trial)

  • elements from young blood

  • hypothalamus regeneration

  • trodusquemine (aka MSI-1436) = Novo Biosciences is struggling for funding

  • Underdog Pharmaceuticals - now Cyclarity - clearing arteriosclerosis

  • LNP mRNA to restore heart function by reprogramming T cells to remove fibrotic cells (Jan 2022)

  • carbon nanotubes for atherosclerosis (2020)

  • Mitrix Bio - harvesting healthy mitochondria from a bioreactor for transplant

  • Satellite Bio

  • mRNA delivery of Stemin and YAP5SA to repair hearts (Robert Schwartz) 2022

  • anti-CD47 and other immune system activating treatments

  • iNKT cell reinvigoration via galactosylceramide (2018)

  • SeNBD (May 2021)

  • MuTaTo (2019)

  • metarrestin - preventing metastasis - now in a phase I clinical trial (2021)

  • Hadiyah-Nicole Green (nano-particles with laser therapy) Ora Lee Smith Center (2020) trying to crowdfund there was another group that reported results with this... from Wales maybe?

  • PRL3-zumab humanized antibody binds PRL3 thereby inhibiting tumors, phase II clinical trial (2021)

  • GP532 a TLR5 agonist, Andrei Gudkov (2021)

  • MR1 (Enara Bio) (universal anti-cancer T cell therapy) (2020)

  • T cells: BAFT upregulation

  • allogenic iNKT (invariant natural killer) cells, Yang Lab (2021)

  • nanoparticles from maize (2022)

  • aspirin could cut risk of death in cancer

  • ELANE/PPE (2021, Becker, Onchilles Pharma)

  • Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors (2022, Nash and Veish) (drug factory beads)

  • albumin nanoparticle (2022, Duxin Sun)

  • dostarlimab (PD-1 inhibitor, anti-cancer) (2022)

  • cancer-killing “drug factory” implants ( Veiseh, Avenge Bio) 2022 -LIfT BioSciences N-LIfT

Revisit later:

  • plasminogen supplement? (sea squirt)

Dud list:

  • BLP
  • MKC8866
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