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i_sanitize_my_hands t1_ivxpe30 wrote

I agree with the other commenter and you. It doesn't make sense to have it as a classification. Especially when one of the labels is so vague and a catch all.

A bit more nuanced case with regression or pattern analysis with correlation between symptoms is more interesting. Secondly, how is your data (you don't have to reveal anything sensitive) ? Can one reliably predict death from it as a simple classification? There can be a few cases where it's super obvious but they are not the most informative ones. It's the grey area where most information can be inferred and delivered to experts / docs.

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No_Captain_856 OP t1_ivxpoqw wrote

I have as features the values for gene expression and miRNA production for a specifical type of tumor. I don’t have many patients sadly, having only ~300 samples.

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Pfohlol t1_ivxvk5q wrote

You can treat it is as a binary classification if you introduce an inverse probability weighting adjustment for censoring and certain assumptions are met. There's a big literature here and it's a bit difficult to pin down the single best reference. Here's a paper that discusses censoring-adjusted evaluation of these models using standard binary classification metrics (Blanche 2013 https://pubmed.ncbi.nlm.nih.gov/23794418/)

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Wakeme-Uplater t1_ivxoqy5 wrote

I think you can frame this problem as

  • Regression - how long will the patient survive (because patient can’t be revived), or
  • Time-series classification, perform binary classification on every time steps (don’t forget to add positional/temporal encoding). But I am not familiar these task
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No_Captain_856 OP t1_ivxozt3 wrote

Thanks! I was asked by my supervisor to perform an overall 0/1 classification, but for me it doesn’t make so much sense!

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eyeswideshhh t1_ivxqi6r wrote

No, how would you answer, question like "survival probablity of a patient, 'X' days from admission" with binary classification done at the end of study.

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No_Captain_856 OP t1_ivxre2y wrote

I wouldn’t, in fact it doesn’t make sense for me… however I was asked to do it by my supervisor, so I’m a bit confused

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